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In case you are an adult suffering from major depressive disorder (MDD), a combination therapy, which includes SPRAVATO, may be helpful for you if you belong to the category who have already advanced antidepressant therapy from two or more oral medications and did not benefit from it. This applies more when you are diagnosed with treatment-resistant depression (TRD).
TRD-treatable resistant depression is one of the only conditions for which the FDA has approved a nasal spray. It is an apparatus substance used to provide a dosage. In this case, it acts as an NMDA receptor antagonist that aims to modulate glutamate in a pathway in the brain, which is considered an active ingredient in pharmacology.
It is also worth mentioning that the safety and effectiveness of TRD, in this case, SPRAVATO, have no evidence supporting its functionality for them trying to prevent a situation that may involve self-harm. Moreover, they must be aware that SPRAVATO is not an alternative for the avoidance of confinement but for patients who have good TRD after an initial course of treatment.
For more information, visit: [SPRAVATO Official Website](https://www.spravato.com/what-is-spravato#what-makes-spravato-different)
Remember that SPRAVATO is administered intranasally, and it’s crucial to follow protocols. Using a nasal ketamine spray device is typically self-explanatory, but still, seek guidance from your gynecologist on its usage.
Your medical provider will outline the timing and frequency of your medicine intake and, during the administration of SPRAVATO, inform you what high advisors should take during the medicine course.
To use this medicine, you must limit eating to two hours and drinking one hour before intake to minimize nausea. Remember all the arrangements for having someone transport you home after your appointment. Expect to stay at home for the entire first day after the appointment.
Be particularly gentle with patients who were not fortunate enough to attend an appointment—expect a slightly altered dose. For patients who use nasal sprays of any sort (steroid or otherwise), make sure the spray is primed at least an hour before use. Administer the device; you can spray it only if you’re certain the practicing recommendation is present.
While undergoing treatment that would potentially require you to use any heavy machinery or drive a vehicle on your own, I would highly recommend not doing so for the “next day after treatment.”
Elevated blood pressure is a dangerous side effect, which usually peaks up to roughly four hours after taking the dosage. Safety procedures regarding blood pressure will be performed prior to and after therapy.
Certain symptoms—chest pain, shortness of breath, severe headache, vision problems, or seizures—should be notified right away. Cognitive impairment, in addition to bladder problems, is another bane. If you have issues with thinking, memory, or urination, contact your healthcare provider directly.
SPRAVATO may cause side effects when combined with an oral antidepressant, including dizziness, nausea, and feelings of disconnection.
Discuss all your illnesses with your healthcare provider to ensure SPRAVATO is suitable for your situation.
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